BDBM18419 (3R,5S)-6-{[1-(4-fluorophenyl)-4-(propan-2-yl)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylcarbonyl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4ff

SMILES CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N1CCc2ccccc2C1)-c1ccc(F)cc1

InChI Key InChIKey=KKERRCWFTMXHDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18419   

LigandPNGBDBM18419((3R,5S)-6-{[1-(4-fluorophenyl)-4-(propan-2-yl)-3-(...)
Affinity DataIC50: 10nMAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed