BDBM18417 (3R,5S)-6-({3-[(cyclohexylmethyl)(methyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}oxy)-3,5-dihydroxyhexanoic acid::oxypyrazole, 4dd

SMILES CC(C)c1c(nn(c1OC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1)C(=O)N(C)CC1CCCCC1

InChI Key InChIKey=LEEKGUHBAWHKQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18417   

LigandPNGBDBM18417((3R,5S)-6-({3-[(cyclohexylmethyl)(methyl)carbamoyl...)
Affinity DataIC50: 6.20nMAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed