BDBM18408 (3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-methoxyphenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4u

SMILES COc1cccc(CN(C)C(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)c1

InChI Key InChIKey=GGHHUYDMLMMLKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18408   

LigandPNGBDBM18408((3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-methoxypheny...)
Affinity DataIC50: 21nMpH: 7.2 T: 2°CAssay Description:Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme source...More data for this Ligand-Target Pair
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Date in BDB:
10/16/2007
Entry Details Article
PubMed