BDBM18354 (2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine-3,4,5-triol::N-Propyl-DNJ

SMILES CCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=DUKKBXHYYSHSAI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18354   

TargetLysosomal acid glucosylceramidase(Human)
Hokuriku University

LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)
Affinity DataIC50: 7.00E+5nMpH: 5.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Human)
Hokuriku University

LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)
Affinity DataIC50: 5.60E+4nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM18354((2R,3R,4R,5S)-2-(hydroxymethyl)-1-propylpiperidine...)
Affinity DataKi:  360nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed