BDBM182961 US9670142, A23 4-benzoxazol-2-yl-N-methyl-N-((1R,3S)-3-phenylacetylamino-cyclopentyl)-benzamide

SMILES CN([C@@H]1CC[C@@H](C1)NC(=O)Cc1ccccc1)C(=O)c1ccc(cc1)-c1nc2ccccc2o1

InChI Key InChIKey=GDTRPUMIXXBPOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182961   

TargetFatty acid synthase(Human)
Merck Patent

US Patent
LigandPNGBDBM182961(US9670142, A23 4-benzoxazol-2-yl-N-methyl-N-((1R,3...)
Affinity DataIC50: 300nMpH: 7.0 T: 2°CAssay Description:The biochemical FASN activity testing was performed as 384 well two-time-point kinetic fluorescence intensity assay format in Greiner low volume medi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent