BDBM182950 US9670142, A12 4'-cyano-biphenyl-4-carboxylic acid methyl-((1R,3S)-3-propionylamino-cyclopentyl)-amide

SMILES CCC(=O)N[C@H]1CC[C@H](C1)N(C)C(=O)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=GWGLDWWKDGWDGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182950   

TargetFatty acid synthase(Human)
Merck Patent

US Patent
LigandPNGBDBM182950(US9670142, A12 4'-cyano-biphenyl-4-carboxylic ...)
Affinity DataIC50: 300nMpH: 7.0 T: 2°CAssay Description:The biochemical FASN activity testing was performed as 384 well two-time-point kinetic fluorescence intensity assay format in Greiner low volume medi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent