BDBM182861 US9676728, 11-B b (-)-2-(2,2,2-Trifluoro-1-methoxy-1-(2-methoxy-4,6-dimethylphenyl)ethyl)-1H-benzo[d]imidazole-5-carbonitrile

SMILES COc1cc(C)cc(C)c1C(OC)(c1nc2cc(ccc2[nH]1)C#N)C(F)(F)F

InChI Key InChIKey=JNXUKFKSQBOVHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182861   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM182861(US9676728, 11-B b (-)-2-(2,2,2-Trifluoro-1-methoxy...)
Affinity DataIC50: 4.11E+4nMpH: 7.4 T: 2°CAssay Description:Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM182861(US9676728, 11-B b (-)-2-(2,2,2-Trifluoro-1-methoxy...)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent