BDBM182846 US9149477, Compound 174

SMILES CCC(Nc1ncnc2[nH]cnc12)c1nc2cccc(Cl)c2c(=O)n1-c1c(F)cccc1F

InChI Key InChIKey=XSSYYHQNXNHAIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182846   

LigandPNGBDBM182846(US9149477, Compound 174)
Affinity DataIC50: 45nMAssay Description:Using the method described in US9149477, Example 2, compounds of the invention were tested for inhibitory activity and potency against PI3Kδ, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent

LigandPNGBDBM182846(US9149477, Compound 174)
Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3K-delta using PIP2 as substrate in presence of gamma[32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed