BDBM182844 US9149477, Compound 117

SMILES CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(Cl)c2c(=O)n1-c1cc(F)cc(F)c1

InChI Key InChIKey=TWLUHIZKDUPYPV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 182844   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Icos

US Patent

LigandBDBM182844(US9149477, Compound 117)Copy SMILESCopy InChI

Affinity DataIC50: 12nMAssay Description:Using the method described in US9149477, Example 2, compounds of the invention were tested for inhibitory activity and potency against PI3Kδ, an...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
6/13/2016
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL