BDBM182797 US9145414, 160

SMILES N[C@H]1COCC[C@H]1Nc1nnc(C(N)=O)c(Nc2cccc3n(ccc23)C2CC2)n1

InChI Key InChIKey=CSGWYPONEHTTTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 182797   

TargetTyrosine-protein kinase SYK(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50: 0.380nMpH: 7.5 T: 2°CAssay Description:The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50: 1.40E+3nMpH: 7.5Assay Description:Conditions for assaying the in vitro inhibitory activity of the compound against KDR kinase activity were set with reference to the statement in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
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TargetAurora kinase B(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM182797(US9145414, 160)
Affinity DataIC50: 1.30E+3nMpH: 7.4 T: 2°CAssay Description:The in vitro inhibitory activity of the compound against Aurora B kinase activity was assayed with reference to a method described in patent publicat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent