BDBM18269 8-phenyl-octanecarboxamide peptidomimetic, 27::methyl 2-{5-[(2S,4S,5S,7R)-4-amino-7-(butylcarbamoyl)-5-hydroxy-7-methyl-2-(propan-2-yl)heptyl]-2-tert-butylphenoxy}acetate

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)C[C@H](Cc1ccc(c(OCC(=O)OC)c1)C(C)(C)C)C(C)C

InChI Key InChIKey=PAHLRMVTECRACY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18269   

TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18269(methyl 2-{5-[(2S,4S,5S,7R)-4-amino-7-(butylcarbamo...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandPNGBDBM18269(methyl 2-{5-[(2S,4S,5S,7R)-4-amino-7-(butylcarbamo...)
Affinity DataIC50: 6nMpH: 7.2Assay Description:In vitro binding affinity for human renin at pH 7.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article