BDBM182311 US9145392, 12

SMILES Cn1cc(nc1C1CCN(CC1)c1cc(N)ncn1)-c1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=BKKVTBLCSODBLG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 182311   

TargetRibosomal protein S6 kinase beta-1(Human)
Merck Patent

US Patent
LigandPNGBDBM182311(US9145392, 12)
Affinity DataIC50: 87nMpH: 7.5 T: 2°CAssay Description:P70S6K inhibitor compounds are diluted and plated in 96 well plates. A reaction mixture including the following components is then added to the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
Go to US Patent

TargetRAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase(Human)
Emd Serono Research and Development Institute

Curated by ChEMBL
LigandPNGBDBM182311(US9145392, 12)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Akt (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed