BDBM181740 US9676728, 6-D (-)-2-(1-Amino-2,2,2-trifluoro-1-(2-methoxy-4,6-dimethylphenyl)ethyl)-1H-benzo[d]imidazole-5-carbonitrile

SMILES COc1cc(C)cc(C)c1C(N)(c1nc2cc(ccc2[nH]1)C#N)C(F)(F)F

InChI Key InChIKey=UHLANYZOSFOPQD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181740   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM181740(US9676728, 6-D (-)-2-(1-Amino-2,2,2-trifluoro-1-(2...)
Affinity DataIC50: 1.57E+3nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent