BDBM181697 US9139578, 16

SMILES NS(=O)(=O)NCc1nnc(o1)C(NC(=O)c1ccc(cc1)C(F)(F)F)c1nc2ccc(cc2s1)-c1ccccc1

InChI Key InChIKey=LWUXYCVBCPEPIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 181697   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM181697(US9139578, 16)
Affinity DataIC50: 10nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent