BDBM181680 US9139578, Reference 1, Isomer A::US9139578, Reference 1, Isomer B

SMILES CC(c1nnc(CNS(N)(=O)=O)o1)(c1nc2ccc(cc2s1)-c1ccccc1)S(C)(=O)=O

InChI Key InChIKey=BTLGEOWADLFWKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181680   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM181680(US9139578, Reference 1, Isomer B | US9139578, Refe...)
Affinity DataIC50: 3.75E+3nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM181680(US9139578, Reference 1, Isomer B | US9139578, Refe...)
Affinity DataIC50: 5.20E+3nMpH: 8.0Assay Description:Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent