BDBM181166 US9139529, 9::US9783501, Compound 9

SMILES Cc1cc(Cl)ccc1Oc1nc2ccccc2nc1C(=O)Nc1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=UWEZKPHUCQGNRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 181166   

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181166(US9139529, 9 | US9783501, Compound 9)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM181166(US9139529, 9 | US9783501, Compound 9)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2019
Entry Details
Go to US Patent