BDBM181101 N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)acetohydrazide (12g)

SMILES COc1cc(\C=N\NC(=O)COc2cc(C)nc3n(nc(C)c23)-c2ccccc2)cc(OC)c1OC

InChI Key InChIKey=BYWFIBRCZKTKIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 181101   

TargetEpidermal growth factor receptor(Human)
Beni-Suef University

LigandPNGBDBM181101(N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-...)
Affinity DataIC50: 4.18E+3nMAssay Description:Kinase activity was determined using Kinase-Glo Plus luminescence kinase assay kit according to the manufacturer instructions. The assays depend on t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Beni-Suef University

LigandPNGBDBM181101(N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-...)
Affinity DataIC50: 8.37E+3nMAssay Description:Kinase activity was determined using Kinase-Glo Plus luminescence kinase assay kit according to the manufacturer instructions. The assays depend on t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Beni-Suef University

LigandPNGBDBM181101(N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-...)
Affinity DataIC50: 8.20E+3nMAssay Description:Kinase activity was determined using Kinase-Glo Plus luminescence kinase assay kit according to the manufacturer instructions. The assays depend on t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Beni-Suef University

LigandPNGBDBM181101(N-(3,4,5-trimethoxybenzylidene)-2-(3,6-dimethyl-1-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Kinase activity was determined using Kinase-Glo Plus luminescence kinase assay kit according to the manufacturer instructions. The assays depend on t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2016
Entry Details Article
PubMed