BDBM180823 US9133171, 28

SMILES COc1cc(F)ccc1-c1nc(Nc2cc(Br)cc(CS(C)(=O)=NC#N)c2)ncc1F

InChI Key InChIKey=DEQKSXYLYYLTSY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 180823   

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180823(US9133171, 28)
Affinity DataIC50: 2nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180823(US9133171, 28)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 2(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180823(US9133171, 28)
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
US Patent