BDBM18014 5-(4-{[(3,4-dichlorophenyl)methyl]amino}phenyl)-6-ethylpyrimidine-2,4-diamine::6-ethyl-2,4-diaminopyrimidine-based compound, 3

SMILES CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=RBIUIGNTQJKKIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18014   

TargetRenin(Human)
Pfizer

LigandPNGBDBM18014(5-(4-{[(3,4-dichlorophenyl)methyl]amino}phenyl)-6-...)
Affinity DataIC50: 2.70E+4nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM18014(5-(4-{[(3,4-dichlorophenyl)methyl]amino}phenyl)-6-...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed