BDBM179827 US9676712, 1C

SMILES O[C@H](CCCCc1ccccc1)\C=C\[C@H]1CCC(=O)N1CCCCCCC(O)=O

InChI Key InChIKey=DEQPIOBZNPCKJE-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179827   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM179827(US9676712, 1C)
Affinity DataEC50:  1.37nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μL of reduced serum medium containing 0.5% FBE. Place ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM179827(US9676712, 1C)
Affinity DataEC50:  0.0140nMAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM179827(US9676712, 1C)
Affinity DataEC50: >1.00E+3nMAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 μl of reduced serum medium containing 0.5% FBS. Place ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

US Patent
LigandPNGBDBM179827(US9676712, 1C)
Affinity DataKi:  3.80nM IC50: 10nMpH: 6.0Assay Description:200 μl in 96-well plate. Cell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3H]PGE2 in the absence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
Go to US Patent