BDBM179741 US9127005, CTH Racemic mixture::US9127005, P1P

SMILES Fc1ccc(cc1)[C@H]1CNC(=O)C11CCN(CCNC(=O)c2cnc3ccccc3c2)CC1

InChI Key InChIKey=BAHMBPJZGYBLIO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 179741   

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 1.97E+3nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 2.00E+4nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 450nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 5.05E+3nMAssay Description:In one aspect, the compound inhibits PLD activity; that is, a compound can inhibit PLD1 activity and/or PLD2 activity. In a further aspect, the compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPhospholipase D2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 450nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt University

US Patent
LigandPNGBDBM179741(US9127005, CTH Racemic mixture | US9127005, P1P)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed