BDBM179703 US9127001, 8j::US9598410, Compound 8j

SMILES Fc1ccc(Cn2nc(c3CN(CCc23)C(=O)C2CCCC2)-c2cccc(c2)C#N)c(F)c1

InChI Key InChIKey=RKVFAILLBWRFDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 179703   

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179703(US9127001, 8j | US9598410, Compound 8j)
Affinity DataIC50: 722nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179703(US9127001, 8j | US9598410, Compound 8j)
Affinity DataIC50: 722nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent