BDBM179683 US9127001, 6bl::US9127001, 6bm::US9598410, Compound 6bm

SMILES CCC(c1ccc(Cl)cc1)n1nc(c2CN(CCc12)C(C)=O)-c1ccc(F)cc1

InChI Key InChIKey=MSZDGTUPPMSZMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 179683   

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179683(US9127001, 6bm | US9127001, 6bl | US9598410, Compo...)
Affinity DataIC50: 966nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179683(US9127001, 6bm | US9127001, 6bl | US9598410, Compo...)
Affinity DataIC50: 251nMT: 2°CAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2016
Entry Details
Go to US Patent

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179683(US9127001, 6bm | US9127001, 6bl | US9598410, Compo...)
Affinity DataIC50: 966nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetPotassium channel subfamily K member 3(Human)
Sanofi

US Patent
LigandPNGBDBM179683(US9127001, 6bm | US9127001, 6bl | US9598410, Compo...)
Affinity DataIC50: 251nMAssay Description:Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent