BDBM179474 US9675697, Cpd. No. 25
SMILES COc1cc6c(cc1c2c(C)noc2C)[nH]c5ccnc(c3c(C)[nH]nc3c4ccccc4)c56
InChI Key InChIKey=ZJTYXGWJNWESQV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 179474
TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 41nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 21nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 42nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 60nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKd: 36nMpH: 7.4Assay Description:Biotin labeled BRD proteins (10 μg/ml) in kinetic assay buffer (PBS, pH 7.4, 0.1% BSA and 0.01% Tween-20) were immobilized on Super Streptavidin...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [326-398](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 9.40nM ΔG°: -10.9kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3 [51-123](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 10nM ΔG°: -10.9kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [91-163](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 12nM ΔG°: -10.8kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 22nM ΔG°: -10.4kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [75-147](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 27nM ΔG°: -10.3kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2 [364-436](Human)
The Regents of The University of Michigan
US Patent
The Regents of The University of Michigan
US Patent
Affinity DataKi: 38nM ΔG°: -10.1kcal/moleT: 2°CAssay Description:Fluorescence Polarization (FP) competitive binding studies (see above) were carried out using the FAM labeled fluorescent probe Cpd. No. 350 to deter...More data for this Ligand-Target Pair