BDBM17851 3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-2-yl)pyridine-2-carboxamide::pyridine-2-carboxylic acid inhibitor, 4

SMILES CC(C)C=Nc1cccnc1C(=O)Nc1nccs1

InChI Key InChIKey=FSYKBCHJLUIEBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17851   

TargetMethionine aminopeptidase 1(Human)
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50: 6.40E+3nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Johns Hopkins University

LigandPNGBDBM17851(3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...)
Affinity DataIC50: 1.00E+6nMpH: 7.5 T: 2°CAssay Description:The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2007
Entry Details Article
PubMed