BDBM17817 imidazopyridine-urea, 44::methyl N-{6-[4-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1H-imidazo[4,5-b]pyridin-2-yl}carbamate

SMILES COC(=O)Nc1nc2ncc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)cc2[nH]1

InChI Key InChIKey=NAHMZQCMCNMUAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17817   

LigandPNGBDBM17817(methyl N-{6-[4-({[2-fluoro-5-(trifluoromethyl)phen...)
Affinity DataIC50: 5.40nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Gsk

LigandPNGBDBM17817(methyl N-{6-[4-({[2-fluoro-5-(trifluoromethyl)phen...)
Affinity DataIC50: 130nMAssay Description:The assay uses purified GST-Tie-2 or GST-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium cryptate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed