BDBM178123 (2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahydrospiro[benzo[d][1,2,3]triazole-4,2'-oxiran]-7-yl isopropylcarbamate (31a)

SMILES COc1ccc(Cn2nnc3[C@@H](CC[C@]4(CO4)c23)OC(=O)NC(C)C)cc1

InChI Key InChIKey=DRCAZLUXFADXPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 178123   

TargetMethionine aminopeptidase 2(Human)
German Cancer Research Center (Dkfz)

LigandPNGBDBM178123((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...)
Affinity DataIC50: 220nMpH: 7.5Assay Description:Stock solutions for all assays were prepared in DMSO (10 mM) and stored at −20 °C. Assays were performed in 96 well plates (Greiner) at a total...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
German Cancer Research Center (Dkfz)

LigandPNGBDBM178123((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...)
Affinity DataIC50: 220nMAssay Description:Inhibition of C-terminal His-tagged human MetAP2 expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
German Cancer Research Center (Dkfz)

LigandPNGBDBM178123((2'R*,7R*)-3-(4-methoxybenzyl)-3,5,6,7-tetrahy...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human MetAP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed