BDBM178061 1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(4-fluorophenyl)-1,2-dihydropyridin-2-one (4)

SMILES COc1cc2nccc(Oc3ccc(cc3)-n3cccc(-c4ccc(F)cc4)c3=O)c2cc1OC

InChI Key InChIKey=QLZRORBVAZHNIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 178061   

TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science & Technology

LigandPNGBDBM178061(1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(4...)
Affinity DataIC50: 100nMpH: 7.4Assay Description:The substrate of poly (Glu, Tyr) 4:1 (20 lg/mL) (Sigma, St. Louis, MO, USA) was precoated in 96-well ELISA plates, and the kinase was incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed