BDBM17781 CHEMBL65860::butane-1,2,4-tricarboxylic acid::carboxylate, 42

SMILES C(CC(=O)O)[C@H](CC(=O)O)C(=O)O

InChI Key InChIKey=LOGBRYZYTBQBTB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17781   

LigandPNGBDBM17781(CHEMBL65860 | butane-1,2,4-tricarboxylic acid | ca...)
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM17781(CHEMBL65860 | butane-1,2,4-tricarboxylic acid | ca...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Glutamate carboxypeptidase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed