BDBM177780 US10000475, Compound 9::US9120786, 9

SMILES NC(=O)c1nc(nc(n1)-c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N1CCOCC1

InChI Key InChIKey=QXYZVVJFACMMAE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177780   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM177780(US9120786, 9 | US10000475, Compound 9)
Affinity DataIC50: 596nMT: 2°CAssay Description:FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
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TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM177780(US9120786, 9 | US10000475, Compound 9)
Affinity DataIC50: 596nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent