BDBM177774 US10000475, Compound 3::US9120786, 3

SMILES FC(F)(F)c1ccc(Oc2ccc(cc2)-c2nc(N[C@H]3CCNC3=O)nc(n2)C#N)nc1

InChI Key InChIKey=FCPYRLPAPSYZRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177774   

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM177774(US9120786, 3 | US10000475, Compound 3)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:FLIPRTETRA Sodium Dye Assay with KCl: Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Purdue Pharma

US Patent
LigandPNGBDBM177774(US9120786, 3 | US10000475, Compound 3)
Affinity DataIC50: 2.00E+4nMAssay Description:The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details
Go to US Patent