BDBM177582 US9120769, 6::US9663470, 6

SMILES COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1ccc2[nH]cnc2c1

InChI Key InChIKey=IGHSTADROFWTPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177582   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM177582(US9120769, 6 | US9663470, 6)
Affinity DataIC50: 296nMpH: 6.0Assay Description:n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM177582(US9120769, 6 | US9663470, 6)
Affinity DataIC50: 296nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent