BDBM17758 (2R)-2-(phosphonomethyl)pentanedioic acid::(R)-2-PMPA::pentanedioic acid analogue, (R)-1

SMILES OC(=O)CC[C@@H](CP(O)(O)=O)C(O)=O

InChI Key InChIKey=ISEYJGQFXSTPMQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17758   

TargetGlutamate carboxypeptidase 2 [44-750](Human)
Guilford Pharmaceuticals

LigandPNGBDBM17758(pentanedioic acid analogue, (R)-1 | (2R)-2-(phosph...)
Affinity DataIC50: 30nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed
TargetGlutamate carboxypeptidase 2(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM17758(pentanedioic acid analogue, (R)-1 | (2R)-2-(phosph...)
Affinity DataKi:  30nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed