BDBM17753 (2R)-2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)methyl]phosphoryl}methyl)pentanedioic acid::(2R)-2-{[hydroxy(pentafluorobenzyl)phosphoryl]methyl}pentanedioic acid::pentanedioic acid analogue, (R)-2

SMILES OC(=O)CC[C@@H](CP(O)(=O)Cc1c(F)c(F)c(F)c(F)c1F)C(O)=O

InChI Key InChIKey=SVAHMQCUSNJPRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17753   

TargetGlutamate carboxypeptidase 2 [44-750](Human)
Guilford Pharmaceuticals

LigandPNGBDBM17753((2R)-2-({hydroxy[(2,3,4,5,6-pentafluorophenyl)meth...)
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2007
Entry Details Article
PubMed