BDBM17737 2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({4-[2-(dimethylamino)ethoxy]phenyl}amino)pyrimidin-4-yl]carbamate::2-aminopyrimidine carbamate, 36

SMILES COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(OCCN(C)C)cc3)n2)c(OC)c1

InChI Key InChIKey=PRFGCHAHYIAXCL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17737   

TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2007
Entry Details Article
PubMed
LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50: 4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2007
Entry Details Article
PubMed
LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50: 2.10E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2007
Entry Details Article
PubMed
LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50: 220nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2007
Entry Details Article
PubMed