BDBM176437 US9688710, 36 (S,R,S,R,R)-N,N′-((methylazanediyl)bis(propane-3,1-diyl))bis(4-(4-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)butanamide)

SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C)c(Cc2ccc(CCCC(=O)NCCCN(C)CCCNC(=O)CCCc3ccc(Cc4cc(ccc4C)[C@@H]4O[C@H](SC)[C@@H](O)[C@H](O)[C@H]4O)cc3)cc2)c1

InChI Key InChIKey=PJAPTVIKDGEXOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176437   

TargetSodium/glucose cotransporter 1(Human)
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176437(US9688710, 36 (S,R,S,R,R)-N,N′-((methylazane...)
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Lexicon Pharmaceuticals

US Patent
LigandPNGBDBM176437(US9688710, 36 (S,R,S,R,R)-N,N′-((methylazane...)
Affinity DataIC50: 10nMpH: 7.3Assay Description:Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent