BDBM176358 US9688696, 74

SMILES Cc1ccc(NC(=O)N2CCN(CC2)c2ccc(cc2)-c2noc(n2)C2CC2)c(Cl)c1

InChI Key InChIKey=UNBBXWXFDFZVOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176358   

TargetDiacylglycerol O-acyltransferase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM176358(US9688696, 74)
Affinity DataIC50: 955nMpH: 7.4 T: 2°CAssay Description:DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2018
Entry Details
Go to US Patent