BDBM17591 (2S,3R)-3-amino-2-hydroxy-N-[(1S)-1-(naphthalen-1-yl)ethyl]-5-(propan-2-ylsulfanyl)pentanamide::CHEMBL170271::bestatin-type inhibitor, 6

SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12

InChI Key InChIKey=HQRKQOZKBUIGKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 17591   

TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17591(CHEMBL170271 | (2S,3R)-3-amino-2-hydroxy-N-[(1S)-1...)
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17591(CHEMBL170271 | (2S,3R)-3-amino-2-hydroxy-N-[(1S)-1...)
Affinity DataIC50: 1.20E+4nMpH: 7.4 T: 2°CAssay Description:A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details
PubMed
TargetMethionine aminopeptidase 2(Human)
Abbott Laboratories

LigandPNGBDBM17591(CHEMBL170271 | (2S,3R)-3-amino-2-hydroxy-N-[(1S)-1...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against human methionine aminopeptidase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine aminopeptidase 1(Human)
Abbott Laboratories

LigandPNGBDBM17591(CHEMBL170271 | (2S,3R)-3-amino-2-hydroxy-N-[(1S)-1...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against human methionine aminopeptidase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed