BDBM175797 US9688683, 78

SMILES COc1ccc(cc1F)-c1ncc2c(n1)N(CC21CC1)c1cccc(OC(=O)N(C)C)c1

InChI Key InChIKey=QLNMMSOXDRRUIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175797   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
GrÜNenthal

US Patent
LigandPNGBDBM175797(US9688683, 78)
Affinity DataIC50: 5.50E+3nMpH: 7.8 T: 2°CAssay Description:The test compound or water (control) is mixed with the human recombinant PDE4B1 enzyme (4.8 U) in a buffer consisting of 44.4 mM tris-HCl, 5.28 mM Mg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2018
Entry Details
Go to US Patent