BDBM175403 1,3-Dimethyl-8-[{3-(2-(homoveratrylamino)-2-oxoethoxy)-4-methoxy}-phenyl]xanthine (16i, RB-412)

SMILES COc1ccc(CCNC(=O)COc2cc(ccc2OC)-c2nc3n(C)c(=O)n(C)c(=O)c3[nH]2)cc1OC

InChI Key InChIKey=LTDQAWJREJGEPO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 175403   

TargetAdenosine receptor A2a(Human)
Panjab University

LigandPNGBDBM175403(1,3-Dimethyl-8-[{3-(2-(homoveratrylamino)-2-oxoeth...)
Affinity DataKi:  772nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Panjab University

LigandPNGBDBM175403(1,3-Dimethyl-8-[{3-(2-(homoveratrylamino)-2-oxoeth...)
Affinity DataKi: >3.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Panjab University

LigandPNGBDBM175403(1,3-Dimethyl-8-[{3-(2-(homoveratrylamino)-2-oxoeth...)
Affinity DataKi: >3.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAdenosine receptor A3 [I248L](Human)
Panjab University

LigandPNGBDBM175403(1,3-Dimethyl-8-[{3-(2-(homoveratrylamino)-2-oxoeth...)
Affinity DataKi: >3.00E+4nMAssay Description:Dissociation constants at A1, A2A and A3 receptors (Ki-values) were determined in radioligand competition experiments as reported earlier [19,20]. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed