BDBM175259 US9115140, I-180

SMILES COc1ccccc1-c1c(sc2cnc(Nc3cc4CCCC(=O)N(C)c4cc3OC(C)C)nc12)C(N)=O

InChI Key InChIKey=FIIRQJNNELJJPZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 175259   

TargetALK tyrosine kinase receptor(Human)
Sanofi

US Patent
LigandPNGBDBM175259(US9115140, I-180)
Affinity DataIC50: 310nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details
Go to US Patent

TargetALK tyrosine kinase receptor [L1196M](Human)
Sanofi

US Patent
LigandPNGBDBM175259(US9115140, I-180)
Affinity DataIC50: 424nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2016
Entry Details
Go to US Patent