BDBM175238 US9115082, 7

SMILES OC(CNCC(=O)N1CCCC1C#N)COc1ccccc1

InChI Key InChIKey=IRTKELPEZOBDMX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 175238   

TargetDipeptidyl peptidase 4(Human)
TBA

US Patent
LigandPNGBDBM175238(US9115082, 7)
Affinity DataIC50: 1nMpH: 4.0Assay Description:The proteolytic enzyme, Dipeptidyle Peptidase IV (DppIV) was monitored in vitro by the substrate Gly-Pro 4-methoxy-β-naphthylamide while in the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetBeta-1 adrenergic receptor(Human)
TBA

US Patent
LigandPNGBDBM175238(US9115082, 7)
Affinity DataKi:  9.83E+3nM IC50: 1.70E+4nMpH: 7.4Assay Description:Human recombinant adrenergic β1 receptors expressed in CHO-K1 cells are used in modified Tris-HCl buffer pH 7.4. A 25 aliquot is incubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetBeta-2 adrenergic receptor(Human)
TBA

US Patent
LigandPNGBDBM175238(US9115082, 7)
Affinity DataKi:  2.20E+4nM IC50: 3.20E+4nMpH: 7.4Assay Description:Human recombinant adrenergic β2 receptors expressed in CHO cells are used in modified Tris-HCl buffer pH 7.4. A 50 aliquot is incubated with 0.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent