BDBM175083 US9115102, Ex14::US9115102, Ex24

SMILES Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1

InChI Key InChIKey=PNRXTCCMSJTZGK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 175083   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 35nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 88nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetInterstitial collagenase(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 2.61E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetStromelysin-1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 6.83E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetMatrix metalloproteinase-9(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 9(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 5.80E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175083(US9115102, Ex24 | US9115102, Ex14)
Affinity DataIC50: 35nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent