BDBM175076 US9115102, Ex2

SMILES CC#CCOc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO

InChI Key InChIKey=GHBQSNPRMVUGFE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 175076   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 28nMpH: 7.4Assay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel, 2006, 19, 155-161) and is added so as to hav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetInterstitial collagenase(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetStromelysin-1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 6.31E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetMatrix metalloproteinase-9(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 1.00E+4nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetDisintegrin and metalloproteinase domain-containing protein 9(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 3.25E+3nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
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TargetDisintegrin and metalloproteinase domain-containing protein 10(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 942nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM175076(US9115102, Ex2)
Affinity DataIC50: 28nMAssay Description:The molecules are tested in dose-response studies on the following enzymes MMP1, MMP3, MMP9, ADAMS and ADAM10 according to the same protocol as that ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details
Go to US Patent