BDBM173616 5-chloro-1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (II)

SMILES OC[C@H]1O[C@H](C(O)[C@H]1O)n1cc(Cn2cc(Cl)c(=O)[nH]c2=O)nn1

InChI Key InChIKey=ZIRCCHHEDZHGHH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173616   

TargetNon-secretory ribonuclease(Human)
University of Thessaly

LigandPNGBDBM173616(5-chloro-1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxyme...)
Affinity DataKi:  4.54E+5nM ΔG°:  -4.63kcal/mole IC50: 5.35E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed