BDBM173613 9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]adenine (12a)

SMILES NC1=NC=NC2C1N=CN2[C@@H]1O[C@H](CO)[C@@H](C1O)n1cc(Cn2ccc(=O)[nH]c2=O)nn1

InChI Key InChIKey=IULRGQCBGUFQMB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173613   

TargetNon-secretory ribonuclease(Human)
University of Thessaly

LigandPNGBDBM173613(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  4.26E+5nM ΔG°:  -4.67kcal/mole IC50: 6.52E+5nMT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetRibonuclease pancreatic(Bovine)
University of Thessaly

LigandPNGBDBM173613(9-[3'-[4-[(Uracil-1-yl)methyl]-1,2,3-triazol-1...)
Affinity DataKi:  1.06E+5nM ΔG°:  -5.51kcal/moleT: 2°CAssay Description:The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed