BDBM173561 1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)phenyl)-3-(4-nitrophenyl) thiourea (18)

SMILES Oc1c(C(c2ccc(NC(=S)Nc3ccc(cc3)[N+]([O-])=O)cc2)c2c(O)c3ccccc3oc2=O)c(=O)oc2ccccc12

InChI Key InChIKey=WKOASWASCLNPSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173561   

TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Universiti Teknologi Mara

LigandPNGBDBM173561(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 2.47E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme inhibition was evaluated according to the method previously reported by Taha et al. with slight modification. Various concentration of tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetDNA polymerase beta(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173561(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of DNA polymerase beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed