BDBM173547 1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)phenyl)-3-(2-chlorophenyl)-thiourea (4)

SMILES COc1ccccc1NC(=S)Nc1ccc(cc1)C(c1c(O)c2ccccc2oc1=O)c1c(O)c2ccccc2oc1=O

InChI Key InChIKey=DRLJBEMMJPPNPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173547   

TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Universiti Teknologi Mara

LigandPNGBDBM173547(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 1.05E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme inhibition was evaluated according to the method previously reported by Taha et al. with slight modification. Various concentration of tes...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM173547(1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Baker's yeast alpha-glucosidase using pNPG as substrate assessed as release of p-nitrophenol preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed