BDBM173502 US9238653, Table 5, Compound 35

SMILES Cc1nc2nc(C)cc(Nc3ccc(cc3)S(F)(F)(F)(F)F)n2n1

InChI Key InChIKey=ZWPHIRBXHOJSHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173502   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Texas

US Patent
LigandPNGBDBM173502(US9238653, Table 5, Compound 35)
Affinity DataIC50: 510nMpH: 8.0Assay Description:For studying inhibition of Plasmodium or human DHODH enzyme, two assays that are in routine use are described, for example, in Baldwin, et al. (2002)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
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