BDBM173480 US9096606, 17

SMILES CO[C@]13CC[C@@]4(C[C@@H]1COCc2cccc(C)c2)[C@H]5Cc7ccc(O)c8O[C@@H]3[C@]4(CC[N+]5(C)CC6CC6)c78

InChI Key InChIKey=AKPVGOXFKIVLEA-UHFFFAOYSA-O

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173480   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173480(US9096606, 17)
Affinity DataKi:  0.290nM ΔG°:  -12.1kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kippa opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173480(US9096606, 17)
Affinity DataKi:  4.30nM ΔG°:  -12.4kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for -opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent